The IC50 increased 1

The IC50 increased 1.7-fold to 8.1 nM (95% CI = 7.4-8.9 nM). by FVL. The reduced threshold was overcome Vilazodone with higher concentrations of TF or FXa progressively. Plasma assays using anti-TFPI antibodies or a TFPI peptide that binds and inhibits FVa, proven that the reduced activation threshold resulted from decreased TFPI inhibition of prothrombinase.… Continue reading The IC50 increased 1