Monoubiquinated ID complex helps in the recruitment of downstream repair proteins, including FancD1/BRCA2, FancS/BRCA1, FancN/Palb2, FancR/Rad51, and FancJ/BRIP1

Monoubiquinated ID complex helps in the recruitment of downstream repair proteins, including FancD1/BRCA2, FancS/BRCA1, FancN/Palb2, FancR/Rad51, and FancJ/BRIP1. Serine 565 occurs downstream of monoubiquitination and inhibit FancD2 deubiquitination.(TIF) ppat.1007442.s001.tif (714K) GUID:?35617411-A29C-444C-A62F-5067E88C9327 S2 Fig: E6 expressing cells showed high Ub-FANCD2 & -FANCI both at baseline and after cisplatin/ MMC treatment. (A-B) Confirmation of HPV16 E6 and… Continue reading Monoubiquinated ID complex helps in the recruitment of downstream repair proteins, including FancD1/BRCA2, FancS/BRCA1, FancN/Palb2, FancR/Rad51, and FancJ/BRIP1