The specificity was high ( 98%) for IgG and IgM antibody

The specificity was high ( 98%) for IgG and IgM antibody. mass screening could help us return to normalcy more quickly. strong class=”kwd-title” Keywords: close contacts, diagnostics capacity, mass screening, SARS-CoV-2 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019, which experienced highly transmissible and pathogenic?[1,?2]. On 30 January 2020, the World Health Organization (WHO) declared the outbreak of novel coronavirus as a general public health emergency of international concern (PHEIC), mainly based on that the number of infected people in China has increased and the outbreak has occurred in several countries?[3]. On 11 February 2020, the WHO named coronavirus disease 2019 (COVID-19), which seriously threatens human health and general public security?[4]. On 11 March 2020, the WHO PB1 officially characterized COVID-19 as a global pandemic?[5]. To data, the novel coronavirus disease COVID-19 has rapidly spread to over 200 countries, areas and territories. Globally, there have been more than 214 million confirmed cases of COVID-19 and more than four million death cases. At present, different countries have developed strategies to deal with the COVID-19 pandemic that fit their epidemiological situations, capacities, and values. Global COVID-19 prevention and control strategies mainly include containment, mitigation and suppression strategies. China mainly taken containment and suppression strategies, which effectively halted the transmission of SARS-CoV-2?[6]. Nonpharmaceutical interventions (NPIs) have been widely used to control the transmission of COVID-19 all over the world, which were essential components of the government response to outbreaks?[7], [8], [9]. These have included patient isolation, contact tracing, contact isolation, travel restrictions, wearing face masks, cancellation of mass gatherings, closure of colleges and expanding interpersonal distancing?[10], [11], [12]. All the measures were aimed at reducing COVID-19 transmission and returning to normal life. Screening of reported symptomatic cases and tracing their contacts aims to provide a more targeted measure, but on numerous occasions, it was hard to effectively control the transmission of COVID-19?[13,?14]. Fast and common identification of infectious people is crucial to fighting against the outbreak of COVID-19. Over the past year, the ongoing pandemic has overwhelmed screening capacity and facilities. When the COVID-19 outbreak occurs, we can identify close contacts of confirmed cases through epidemiological investigation. However, mass screening has been progressively used to detect suspected COVID-19 cases and their close contacts, asymptomatic case, patients attending fever clinics, high-risk populations, employees, even all populace to identify infectious individuals. Although, screening on its own will not quit the spread of SARS-CoV-2, as part of a strategy, screening integrated with following isolation of TH588 hydrochloride those with positive test results in Beijing and Qingdao city have managed to control the common transmission of SARS-CoV-2 computer virus. Here we describe the history of mass screening, define the scope of mass screening, describe its application scenarios, and TH588 hydrochloride discuss the impact and difficulties of using this approach to control COVID-19. We conclude that through a comprehension screening program and strong screening capabilities, mass screening could help us return to normalcy more quickly. The development TH588 hydrochloride of screening The commission rate on chronic illness conference on preventive aspects of chronic disease held in 1951?[15], defined screening as the presumptive identification of unrecognized disease or defect by the application TH588 hydrochloride of assessments, examinations, or other procedures which can be applied rapidly. Screening assessments sort out apparently well persons who probably have a disease from those who probably do not. A screening test is not intended to be diagnostic. Persons with positive or suspicious findings must be referred to their physicians for diagnosis and necessary treatment. In general, it had taken the definition to imply a relatively simple (though not necessarily unsophisticated) method of case-finding. According to the form of the screening, the screening can be divided into mass screening, selective screening, and multiple screening. Mass screening is usually a term used to indicate the large-scale screening of whole populace groups?[15]. It referred to screening where no selection of populace groups is made. Selective screening is used for the screening of selected high-risk groups in the population. It may still be large-scale, and can be considered as one form of populace screening. Multiple screening has evolved by combining single screening assessments. Where much time and effort has been spent by a populace in attending for a single test. It is natural to consider the economy of offering other tests at the same time. Multiple screening has been defined as the application of two or more screening assessments in combination.